Skip to content

조회 수 26691 추천 수 0 댓글 0
?

단축키

Prev이전 문서

Next다음 문서

크게 작게 위로 아래로 댓글로 가기 인쇄 수정 삭제
?

단축키

Prev이전 문서

Next다음 문서

크게 작게 위로 아래로 댓글로 가기 인쇄 수정 삭제
http://www.nationalpost.ca/search/site/story.asp?id=AACD21F3-42EC-40D6-B2D3-F283B55D12C3

다는 이야깁니다.

An aspirin a day keeps cancer at bay
Confluence of 3 studies

Saturday » March 8 » 2003


Brad Evenson 
National Post


Thursday, March 06, 2003

New research on Aspirin, a centuries-old drug once extracted from willow bark, shows a single pill a day dramatically cuts the risk of cancer.

Doctors already recommend the drug to protect the heart, prevent strokes and reduce the pain from arthritis. But three new studies, two published today in the New England Journal of Medicine, demonstrate the drug also has potent anti-cancer properties.

In one of two U.S. studies of patients with previous colorectal cancer, 37% fewer patients who took Aspirin developed adenomas compared to patients who got placebos. Adenomas are precursors to cancer and are often called polyps.

The benefits were so striking the study was halted early so all the patients could take the medicine.

''From both animal research and observational studies, we've recognized for a long time that Aspirin might decrease the risk of colon cancer,'' said Dr. Robert S. Sandler, the study's principal investigator.

''To find out whether Aspirin really worked, we needed a randomized trial where we could compare Aspirin with a placebo.''

In a separate finding, Italian scientists reported in the British Journal of Cancer this week that taking Aspirin for five years cuts the risk of cancers of the mouth, throat and esophagus by two-thirds. The researchers say if people started taking the drug earlier, specifically for its anti-cancer properties, it might be possible to achieve even stronger protective effects.

''This is the first quantitative evidence that taking Aspirin may reduce the risk of developing cancers in what we call the aerodigestive tract, connecting the mouth and the stomach,'' said lead researcher, Cristina Bosetti of the Institute of Pharmacological Research in Milan.

Scientists began looking at Aspirin as an anti-cancer agent in the early 1990s, when they found regular users, such as arthritis sufferers, had less cancer than usual. The current studies are the first large-scale trials to provide direct evidence that Aspirin was responsible.

Previous studies using drugs, dietary fibre or vitamins to prevent adenomas have not had a significant effect.

Aspirin works by blocking an enzyme called COX-2 that controls inflammation.

This enzyme is also produced by colon tumours, leading to faster cell growth, increased capacity to invade healthy tissue and growth of new blood vessels to feed tumours. Drugs such as Celebrex and Vioxx, which also inhibit COX-2, have also shown signs of being cancer fighters and studies are now being conducted.

''The good news is that ... sometimes, the best chemopreventive agents are close at hand, and relatively inexpensive,'' said Electra Paskett, co-author of one study and associate director of population sciences at the Ohio State University Comprehensive Cancer Center.

In the first study, 719 patients with a history of colorectal cancer were observed from 1993 to 2000 in hospitals across the United States. Among those who took a daily, 325-milligram dose of Aspirin, 17% developed adenomas compared with 27% in the placebo group.

In the second study, 1,100 patients with previous colorectal polyps were studied from 1994 until 2001. Patients got either a baby Aspirin of 81 mg, or 325 mg, or a placebo. Interestingly, the group receiving the baby Aspirin showed a lower incidence of recurring polyps than did those treated with the larger dose.

According to the National Cancer Institute, an estimated 17,600 Canadians were diagnosed with colorectal cancer last year and 6,600 died of the disease. Since the studies show Aspirin protects against pre-cancerous polyps, it probably also reduces the rate of colorectal cancer itself.

Researchers said although Aspirin is a safe drug, patients should consult a doctor before taking it every day and should get regular checkups.

''Aspirin is not a magic bullet,'' said Dartmouth Medical School researcher John Baron, author of the second study.

''Although the incidence was reduced, all the polyps didn't go away in our study. Regular screenings, perhaps including colonoscopies, are still important.''

bevenson@nationalpost.com
?

Title
List of Articles
번호 제목 글쓴이 날짜 조회 수
공지 글쓰기 및 편집 방법 2 file 다중이 2016.06.12 48013
591 행복한세상~(플래쉬) Jasper 2002.12.29 18029
590 [공지] 인신공격적인 글은 무조건 삭제됩니다 운영자 2003.01.01 17685
589 캘거리전경... jasper 2003.01.01 15901
588 박노자"광화문에 전태일 동상이 세워졌으면" 한겨레 운영자 2003.01.11 9588
587 신간소개 자코 2003.01.22 14986
586 컴퓨터 배경무늬를 만들고 싶습니까? 운영자 2003.02.06 16458
585 캐나다 조선선교史 논문 낸 `흰머리 대학생` 한경섭씨 운영자 2003.02.06 16177
584 적화통일되면 너희 다 죽어!`-19일 시청앞 종교집회 현장 -오 마이 뉴스 운영자 2003.02.09 15990
583 `캔들데이` 첫번째 촛불상 받은 이지선씨-한겨레 운영자 2003.02.12 12667
582 친일과 반공이 보수를 죽였다 - 한겨레 운영자 2003.02.21 11523
581 주한 미군사령관에게 ....... 金大植 운영자 2003.02.21 15812
580 [조선]이 멍석 깔아준 자기비하 -오마이뉴수 운영자 2003.02.21 12684
579 `상습 성희롱` -오마이 뉴스 운영자 2003.02.28 13633
578 엄마 사랑해요...`대구지하철 참사를 추모하며` 오마이뉴스 운영자 2003.02.28 14305
577 박정희와 악마주의- 진중권 운영자 2003.03.02 14072
576 중세인가 포스트모던인가 -진중권   운영자 2003.03.02 10807
575 [대북송금] 노벨상을 돈주고 샀다구?? -딴지일보 운영자 2003.03.02 8849
574 “저 강금실인데요…” `응 뭔데?` ---nate 뉴스 운영자 2003.03.06 8833
» 아스피린을 정기 복용하면 암발생을 줄인다. National Post 운영자 2003.03.08 26691
572 가족 여행 비디오 테잎 의심받아 -YTN 운영자 2003.03.08 9483
571 노무현 대통령과 검사군단 토론 후일담 운영자 2003.03.09 8892
570 [발의] 귀족검사 권력보장을 위한 특별조치법-딴지일보 운영자 2003.03.11 9585
569 부시는 `바보`가 아니다- 오마이뉴스 운영자 2003.03.12 8319
568 향기를 팔지 않는 매화처럼.. (플래쉬) 클루 2003.03.13 8601
567 노엄 촘스키 `제국과의 대결` 강연 링크 [필독) 운영자 2003.03.13 9588
566 스피노자의 신, 스피노자적 재발견-한겨레 운영자 2003.03.14 8708
565 파병 찬반을 떠나 생각해야할 것 - 한겨레 운영자 2003.03.30 8505
564 이라크전, 2차대전후 최대위기 부를 수도` -프레시안 운영자 2003.04.02 12358
563 노무현과 완전한 나라 -한겨레 운영자 2003.04.05 9038
562 `꽃`의 의미... Jasper~ 2003.04.07 8483
목록
Board Pagination Prev 1 2 3 4 5 6 7 8 9 10 ... 20 Next
/ 20

Powered by Xpress Engine / Designed by Sketchbook

sketchbook5, 스케치북5

sketchbook5, 스케치북5

나눔글꼴 설치 안내


이 PC에는 나눔글꼴이 설치되어 있지 않습니다.

이 사이트를 나눔글꼴로 보기 위해서는
나눔글꼴을 설치해야 합니다.

설치 취소